宫颈不典型鳞状细胞与宫颈病变的关系研究

The relationship between atypical squamous cell of undetermined significance and cervical lesion

目的探讨宫颈液基细胞学检查为未明确意义不典型鳞状细胞(Atypical squamouns cell of undetermined significance,ASCUS)与宫颈病变的关系。方法对185例宫颈液基细胞学检查报告为ASCUS患者行阴道镜下多点活检及组织病理学检查,并进行临床与病理的对照分析。结果185例ASCUS患者,活检组织病理学检查结果为炎症者118例,占63.78%,各级宫颈上皮内瘤变(CIN)63例,占34.05%,其中CINⅠ38例,CINⅡ15例,CINⅢ10例。宫颈浸润癌4例,占2.16%。结论ASCUS中,CIN占较大比例,且有宫颈癌可能。因此对ASCUS患者应予以重视,应行阴道镜下活检进一步明确诊断。

Objective To investigate the relationship between atypical squamous cell of undetermined significance （ ASCUS） and the cervical lesion. Methods 185 eases of 2720 patients were diagnosed as ASCUS with liquid based cytology, which were further biopsy under the colposcope. Results 118 cases of patients with ASCUS were determined as inflammation （63.78% ） , 63 cases as CIN（34. 05%） , and 4 cases as cervical invasive cancer（2. 16% ）. Conclusion ASCUS may be the first indication of CIN and cervical invasive cancer. Biopsy under colpscope should be applied on ASCUS.