复方Ca(OH)_2等三种药物防治根管预备后激惹反应的临床研究

A clinical study of compound Ca(OH)_2 etc in the prevent of irritation response after root canal preparation

目的对比观察复方Ca(OH)2、Ca(OH)2及FC三种药物对根管预备后激惹反应的防治效果。方法随机抽取需要做根管治疗的非急性根尖周炎、非急性牙髓炎的口腔门诊患者,分为实验组(A)、对照组(B)及对照组(C),其患牙经常规根管预备后分别放置复方Ca(OH)2、Ca(OH)2及FC三种药物棉捻暂封,并观察术后3 d激惹反应的发生情况。结果本组共完成研究病例531例,其中实验组(A)181例,对照组(B)173例,对照组(C)177例。经过观察统计,3组在术后第3天出现激惹反应的平均发生率分别为9.39%、20.23%、33.90%。实验组(A)、对照组(B)2组[或对照组(B)、对照组(C)组]差异均有显著性(P<0.05),而实验组(A)与对照组(C)则差异有显著性(P<0.001)。结论3组药物防治根管预备后激惹反应的作用强度依次为复方Ca(OH)2>Ca(OH)2>FC,为有效降低根管预备后激惹反应的发生,前两种药物可作为根管内封药的首选。

Objective To compare and observe the effect of compound Ca （OH） 2, Ca （OH）2 and FC in prevention and treatment of irritation response after root canal preparation. Methods Some stomatologieal outpatients with non-acute pulpitis were picked out randomly and then divided up into experimental group （ A ）, control group （ B ） and control group （ C ）. After routine root canal preparation, the affected teeth were sealed with cotton swabs soaked with compound Ca （ OH ） 21 Ca （ OH ） 2 and FC and were observed for three days in terms of the occurring of irritation response. Results 531 eases were studied altogether,including 181 eases in the experimental group （A） , 131 eases in the control group（B） and 177 in the control group （ C ）. Observation and statistics revealed that on the third day after operation the average rate of irritation response of the three groups was 9. 39% ,20. 23% and 33.90% respectively. The difference between group A and B（or between group B and group C ） was obvious （ P 〈 0. 05 ） while the difference between group A and group C was significant （ P 〈 0. 001 ）. Conclusion The three kinds of medicine used for irritation response after root canal preparation can be sequenced as compound Ca（OH）2 〉 Ca （ OH ） 2 〉 FC in therapeutic effect intensity. The first two are preferred as the intracanal medicine after root canal preparation.