八种方案治疗霉菌性阴道炎的成本效果分析

Pharmacoeconomic analysis on 8 plans in the treatment of vaginal mycosis

目的探讨4种治疗方案用于霉菌性阴道炎的药物经济学效果。方法选择2006年1月-2007年6月400例霉菌性阴道炎患者，随机分为8组：A组外用西药治疗，B组口服西药治疗，C组西药外用＋口服治疗，D组外用中药治疗，E组内服中药治疗，F组中药外洗＋内服治疗，G组外用西药＋内服中药治疗，H组外用中药＋内服西药治疗。应用药物经济学中成本-效果分析法是行评价。结果8种治疗方案总有效率分别为75．5％、52．0％、92．2％、75．O％、79．2％、94．0％、96．2％、94．0％；成本／效果（C／E）分别为1．7、0．36、1．6、1．2、．4．5、1．3、2．2、0．54；C、F、G、H组有效率在90％以上，以H组为参照，增加一个效果单位成本-效果比（△C／△E），分别为-5．1、342．5、74．9。结论A、B、D、E组治疗方法有效率低，H组治疗方案（中药外洗十口服氟康唑胶囊）最理想。

Objective To research the economic effect of eight plans for the treatment of vaginal mycosis. Methods Four hundred cases of vaginal mycosis were grouped as A, B, C, D, E, F, G, H at random. A ： external use of western medicine ; B ： oral use of western medicine;C ：oral use of traditional Chinese medieine;F ：external and oral use of traditional Chinese medicine; G： external use of western medicine and oral use of traditional Chinese medicine ; H ： external use of traditional Chinese medicine and oral use of western medicine. Results The total effective rates in all the groups were 75.5% ,52.0% ,92.2% ,75. 0% ,79.2% ,94, 0% ,96.2% and 94.0% respectively C/E were 1.7,0.36,1.6,1.2,4.5,1.3,2.2 and 0.54 respectively. The total effective rates in groups over 90% were C,F,G,H. The △C/△E of A,B,D,E and H were -5.1,342.5,74. 9. Conclusion Group H （ external use of traditional Chinese medicine and oral use of fluconazole capsule ） is the optimal treatment.