AcrySof和PMMA人工晶状体植入致后发性白内障发生率的比较

Comparative incidence of posterior capsular opacification in AcrySof and PMMA intraocular lenses

目的：评价植入聚甲基丙烯酸甲酯（PMMA）人工晶状体和软性人工晶状体（AcroSof）致后发性白内障的严重程度。方法：总共100人（110眼）进行了人工晶状体植入术，随机分为两组植入不同类型的晶状体。组Ⅰ：AcrySof（SA60AT）人工晶状体，组Ⅱ：PMMA（LXIOBD）人工晶状体。分别在术后3，6，12和18mo，通过测定最佳矫正视力和数码照片拍摄评价后囊膜浑浊的密度。结果：术后3mo，PMMA组后囊膜浑浊的密度明显增加（3．6％），而Acrylic组并未发现增加。术后18mo，显著后囊膜浑浊两组的发生率相比较，Acrylic组（14．5％）较PMMA组（34．5％）低。由于PMMA人工晶状体比AcrySof人工晶状体所致后囊膜浑浊的范围广，故其导致更严重的视力降低。结论：与PMMA人工晶状体相比较，植入AcrySof人工晶状体在一定程度上有助于降低后发性白内障的发生率。

AIM： To evaluate the extent of significant posterior capsule opacification （PCO） after implanting polymethylmethacrylate （PMMA） and soft acrylic intraocular lenses. METHODS： A total of one hundred patients （110 eyes） undergoing intraocular lens （IOL） implant surgery were randomly divided into two groups based on the type of IOL＇s implanted. Group Ⅰ： AcrySof （SA60AT） and Group Ⅱ： PMMA （LX10BD）. The density of posterior capsular opacification （PCO） was assessed 3, 6, 12 and 18 months after surgery by taking best corrected visual acuity （BCVA） and the digital photographs. RESULTS： At the end of 3 months postoperatively, the PCO density in the Group Ⅰ （ PMMA ） increased significantly （3.6%） while no increase was found in the Group Ⅱ （Acrylic）. By the end of 18 months follow up, the incidence of significant PCO was found to be less in the acrylic group （14. 5%） as compared to the PMMA group （34.5%）. On the basis of density , the PCO was more extensive with the PMMA lens than the AcrySof lens, which led to more severe visual loss. CONCLUSION： The intraocular implantation of the AcrySof IOL helps to reduce the incidence of PCO to a greater degree as compared to the PMMA IOL.