指长比与乳腺癌的相关性研究

A Study of the Relationship Between Digit Ratio and Breast Cancer

本文研究了宁夏汉族女性256例(正常对照:128例,乳腺癌患者:128例)左右手指长比(2D∶3D、2D∶4D、2D∶5D、3D∶4D、3D∶5D、4D∶5D),比较其均值的差异性;分析了指长比与年龄间的关系。结果表明:1)宁夏汉族正常女性与乳腺癌患者组指长比均值呈现2D∶3D<2D∶4D<3D∶4D<2D∶5D<4D∶5D<3D∶5D的趋势;2)乳腺癌患者组指长比均值均高于正常对照组,2D∶3D(P<0.05)、2D∶4D(P<0.01)、2D∶5D(左手P<0.05)有显著性差异;乳腺癌患者组2D>4D的比例高于对照组;3)乳腺癌患者组指长比均值与发病年龄呈高度负相关(P<0.001)。

Digit ratio （2D：3D; 2D：4D; 2D：5D; 3D：4D; 3D：5D; 4D：5D）ineluding mean values of both hands of 256 women from Ningxia Han nationality （control and breast cancer sample of 128 each） were studied. The relationship between digit ratio and women＇s age was also analyzed, with the following results. 1 ） The mean values of the digit ratio of the healthy control and breast cancer samples presented the following trend - 2D：3D 〈 2D：4D 〈 3D：4D 〈 2D：5D 〈 4D：5D 〈 3D：5D. 2） The breast cancer sample had higher mean values than the control sample. Compared with the control sample, there were significant differences of 2D：3D （ P 〈 0.05）, 2D：4D （ P 〈 0.01）and 2D：5D（left P 〈 0.05）in the breast cancer sample. There was also a higher percentage of 2D 〉 4D in the breast cancer sample. 3） The relationship between 2D：4D （including left hands, fight hands, and the mean values of them） and the women＇s age was significant in the breast cancer sample （P 〈 0.001）.