Schmid型干骺端软骨发育异常X线诊断(附4例报告)

X-ray diagnosis of Schmid type metaphyseal chondrodysplasia:a report of 4 cases

目的探讨Schmid型干骺端软骨发育异常(MCD)的临床表现与X线特征。方法4例临床考虑Schmid型MCD,其中,包括3名年龄为4～11岁的儿童和1名年龄为27岁的成年妇女,于临床症状出现后均经临床观察和X线检查。结果所有4例患者或者是儿童或者是成年妇女临床上均以矮小身材、弓形腿、膝与髋内翻及鸭步态为特征。X线摄影显示,干骺端软骨发育异常的病变主要累及双侧掌指骨、长管状骨以及髋与膝关节。结论Schmid型MCD具有独特的临床表现与X线特征,二者综合分析可以作出准确的诊断与鉴别诊断。

Objective To study the clinical manifestations and X-ray features of Sehmid type metaphyseal ehondrodysplasia （MCD）.Methods Four patients with clinically considered Sehmid MCD, of whom, three children aged 4-11 years and one woman aged 27 years underwent the elinieal observations and radiographie examinations after onset of clinical symptoms. Results All 4 patients either ehildren or adult were clinically eharaeterized by short stature, bowed legs, knee vara, eoxa vara, and a waddling gait. Radiographs showed that the lesions of Sehmid type MCD mainly involved into bilateral metacarpal-finger bones, long tubular bone ,hips and knees. Coclusion Sehmid type MCD has characteristic clinical manifestations and radiographic features,while an overall analysis of the both data can make the accuratediagnosis and differential diagnosis.