大剂量胸腺肽对乙型病毒性肝炎的治疗作用

The Curative Effects of Large Dose Thymosin in Chronic Hepatitis B

本研究选择慢性乙型肝炎（ＣＨＢ）１１０例，分大剂量胸腺肽、干扰素和一般护肝治疗三组。结果表明，大剂量胸腺肽可以促使ＡＬＴ复常，降低血中ＨＢＶＤＮＡ水平，促使ＨＢｅＡｇ和ＨＢＶＤＮＡ阴转，其疗效与干扰素相似，优于一般护肝组，且使用安全，大剂量胸腺肽疗法可作为阻断或抑制ＨＢＶ复制一种新方法。

This study enrolled 110 patients diagnosed as chronic hepatitis B (CHB) according to the diag- nostic criteria. They were divided vnto three groups, namely, the large dose thymosin treatment group (60 pa- tients); the interferon treatment group (30 patients); the ordinary liver protective group (20 patients). After being treated it was found that large dose thymosin could promote the recovery of ALT,reduce the contetnt of HBV DNA ,Promote the seroconversion of HBeAg and HBV DNA. lt's cruative effects were similar to that of interferon, much better than that of the ordinary liver protective, furthermore it was safe. As a result, it was believed that using large dose thymosin for the treatment of HB might be a new therapeutic method.