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可溶性CD40L与急性冠脉综合征的临床研究

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摘要 目的探讨急性冠状动脉综合征(ACS)患者血清可溶性CD40L(sCD40L)水平变化的临床意义。方法应用酶联免疫测定法(ELISA)对正常对照组40例,不稳定心绞痛(UA)42例,急性心肌梗塞(AMI)13例,外周血sCD40L水平进行检测。结果ACS组血清sCD40L水平明显高于对照组(P<0.01),AMI组血清CD40L水平又高于UA组,差异有显著性(P<0.05)。随访期ACS sCD40L增高组心血管事件发生率明显高于正常组(P<0.01)。结论sCD40L水平升高可能与急性冠状动脉综合征的发生有关,是动脉粥样硬化斑块不稳定的标志。
作者 郁小迎 孙兰 王芳 魏文 唐小梅 陈宗宁 顾明标
机构地区 江苏省盐城市第一人民医院
出处 《哈尔滨医药》 2008年第6期13-13,共1页 Harbin Medical Journal
关键词 可溶性CIMOL 急性冠状动脉综合征
分类号 R541.4 [医药卫生—心血管疾病]
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哈尔滨医药
2008年 第6期

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