人脱细胞真皮在腹壁缺损修复中的应用

Application of human acellular dermal matrix in abdominal wall defect repair

目的:探讨人脱细胞真皮(human acellular dermal matrix,HADM)在腹壁缺损修复中的应用。方法:回顾我院外科自2007年5月至2008年9月14例使用HADM修复腹壁缺损病人的临床资料,分析手术效果及并发症的发生率。结果:14例均顺利重建腹壁,无感染及肠梗阻、肠瘘等并发症发生;随访1～16月,无疝复发和其他类型腹壁疝出现。结论;HADM在腹壁缺损的修复上具有一定优势,尤其是在处理感染或污染创面时,是一种值得在临床上推广应用的理想补片材料。

Objective To investigate the effects of human acellular dermal matrix （HADM） in abdominal wall defect repair. Methods Between May 2007 and September 2008, 14 cases of abdominal wall defects were repaired with HADM. The defects were caused by parastomal hernia, ventral hernias, incisional hernias, radical excision of abdominal wall and trans-rectal abdominal myocutaneous （TRAM） tumors. All these cases were followed up for 1-16 months, the rates of recurrence and complications including surgical site infection, immunal reaction, fistula and seroma formation were recorded. Results All the abdominal wall defects were reconstructed successfully. The patients healed without severe complications, such as infection, bowel obstruction or fistula formation and no sign of recurrence of hernia was observed. Conclusions HADM is an ideal material in repairing abdominal wall defect, especially in patients with recent intra- abdominal infections and previous wound infections.