估算法与精确法碘131治疗Grave’s病的疗效研究

Estimation of curative effects of iodine131 on hyperthyroidism

目的研究碘131估算法与精确法治疗甲状腺功能亢进(甲亢)的疗效差别,优化医护人员放射防护。方法对拟碘131治疗的甲亢患者根据挂号单双随机分为两组,分别采用估算法和精确法进行碘治疗,进行疗效分析。结果①精确法和估算法两组病人的性别和年龄差异无显著意义。采用独立样本χ2检验两组性别χ2=0.278,P=0.598,年龄χ2≈37.068,P=0.646。②精确法和估算法总体一次治愈率、好转率、复发率分别为79.4%vs70.7%、19.8%vs28%,0.8%vs1.2%,χ2≈2.061,P=0.560,差异无统计学意义(P>0.05)。结论精确法与估算法对碘131治疗甲亢的疗效一致,采用估算法进行甲亢碘治疗,减少医护人员治疗时间,优化放射防护。

Objective To investigate the differences between estimated method and accurate method in treatment of hyperthyroidism with iodine-131. Methods Patients with hyperthyroidism were randomly divided Estimated Group treated with iodine 131 and Accurate Method Group treated with iodine 131. Effectiveness of the two groups were analyzed. Results There no significant difference in gender and age in two groups （P=0.598） of the gender of the two groups, likelihood ratio was 37.068; （2） cure rate, relief rate and relapse rate of groups after first treatment in accurate and estimated method groups were 79.4% vs 70.7%, 19.8% vs 28%,0.8% vs 1.2%. The likelihood ratio was 2.061（P=0.560）. Conclusion No significant difference were observed in the efficiency of accurate and estimated method.