南京地区肺科患者军团菌感染状况调查

The Status of Legionella Infection in Patients with Pulmonary Diseases in Nanjing

了解南京市不同人群军团菌感染情况。选择南京市健康从业人员和肺科住院患者共计912份血清标本,采用微量凝集试验检测军团菌抗体效价,并对受检者进行流行病学调查。结果显示,南京市肺科患者军团菌抗体阳性率(46.3%,265/572)显著高于健康从业人员阳性率(39.4%,134/340)(P<0.05)。女性阳性率(45%)比男性阳性率(42.9%)稍高,但无显著性差异(P>0.05)。肺科患者中Lp 1型阳性率最高(14.2%),其次为Lp6型(8.9%),Lp 10型最低(0.17%)。健康从业人员中Lp 1型阳性率最高(12.4%),其次为Lp 3型(7.1%),Lp 6型(6.2%)和Lm型(5.0%)较低,Lp9未检出。结果提示,军团菌感染已经成为南京市肺科疾病重要的因素之一,并已对健康从业人员构成潜在危险。

To study the status of Legionella infection in different populations, 912 serum samples were collected from healthy people or patients suffering pulmonary disease in Nanjing. The antibody dilution was detected by micro-agglutination test with antigens of Lp typel-8 and Lm. The results showed that the positive rate of Legionella infection in patients suffering pulmonary disease （46.3%, 265/572） was statistically higher than that of healthy control （39.4%, 134/340） （ P 〈 0.05 ）. The positive rate in female （45%）was slightly higher than that of in male （42.9%）, but there was no statistical difference between them （P 〉 0.05 ）. The positive rate of Lpl （ 14.2 % ） was highest in patients suffering pulmonary disease, followed by Lp 6（8.9 % ）, and Lp 10 was the lowest one （0.17 % ）. In healthy people, the highest infection type was Lp 1 （ 14.2% ）, followed by Lp 3 （7.1%） ,Lp 6 （6.2%） and Lm （5.0%） in tum. The Lp9 was not detected. The results indicate that infection of LegioneUa may be one of the important factors for patients suffering pulmonary disease in Nanjing and the healthy populations were in risk of infection by Legionella.