甲亢患者骨矿物含量与血清PTH、BGP和CT的关系

The Relationship Between Bone Mineral Density and Serum TH,BGP and CT Levels in The Relationship between Bone Mineral Density and Serum PTH,BGP and CT Levels in Patients with Hyperthyroidism

为探讨甲亢患者骨矿物含量(BMD)与血清甲状旁腺激素(PTH)、骨钙素(BGP)和降钙素(CT)的关系,以167例甲亢患者为甲亢组,58名正常人为对照组,测定两组BMD和用RIA测定血清BGP、PTH、CT。结果表明,甲亢组的BMD(0.52±0.21g/cm2)和CT(70.3±12.9ng/L)比正常组(0.79±0.36g/cm2,102.7±27.4ng/L)下降(P<0.01)。甲亢组血清PTH(30.4±9.6ng/L)和BGP(12.6±4.1μg/L)比对照组(22.8±8.1ng/L,6.3±1.1μg/L)升高(P<0.01)。本文提示,甲亢患者的BMD与血清PTH、BGP、CT水平有关。

To explore the relationship between the bone mineral density （BMD） and serum PTH, BGP and CT levels in patients with hyperthyroidism. The serum levels of BGP, CT and PTH in 167 patients with hyperthyroidism and 58 normal controls were determined by RIA. The results showed that the ser- um CT levels and BMD in patients with hyperthyroidism were significantly lower than those in the control group （P 〈 0.01 ）. The serum levels of PTH and BGP in patients were significantly higher than those in the control group （ P 〈 0.01 ）. The BMD in patients with hyperthyroidism was related to the serum levels of PTH, BGP and CT.