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氯胺酮术后硬膜外镇痛对经产妇宫缩痛的影响 被引量:1

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摘要 目的:探讨氯胺酮与吗啡用于术后硬膜外镇痛对经产妇宫缩痛的影响。方法:抽取ASAⅠ~Ⅱ级,年龄为25~35岁经产妇90例,随机分成吗啡组(M组)、氯胺酮1组(K1组)和氯胺酮2组(K2组),每组各30例。3组镇痛液配方分别为吗啡5mg、氯胺酮0.5mg/kg、氯胺酮1.0mg/kg各加左旋布比卡因112.5mg、地塞米松10.0mg生理盐水稀释至100ml,观察术后1、6、12、24和48h经产妇的VAS评分、产后阴道出血量及呼吸抑制、恶心呕吐瘙痒和噩梦发生率。结果:K2组经产妇6、12和24hVAS评分与M组和K1组VAS评分比较差异均有显著性(P<0.01)。K1及K2组经产妇术后恶心呕吐和瘙痒发生率较M组经产妇显著降低(P<0.01),3组间呼吸抑制和噩梦发生率及产后阴道出血量比较差异无显著性(P>0.05)。结论:氯胺酮术后硬膜外镇痛能有效减轻产妇术后宫缩痛,不良反应轻,安全可靠,其作用优于吗啡。
出处 《南京医科大学学报(自然科学版)》 CAS CSCD 北大核心 2008年第12期1644-1645,共2页 Journal of Nanjing Medical University(Natural Sciences)
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