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Survivin基因与恶性肿瘤的研究进展 被引量:6

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摘要 Survivin是近年来发现的一种肿瘤凋亡抑制蛋白。其在恶性肿瘤的表达具有高度特异性,高表达于几乎所有恶性肿瘤组织,而在正常成人组织中未见表达。Survivin在肿瘤发生、发展过程中起重要作用,已成为肿瘤治疗的新靶点。本文介绍了Survivin的分子生物学结构、分布、作用机制、功能及其在恶性肿瘤的诊断、治疗及预后中的关系。
出处 《实用肿瘤学杂志》 CAS 2008年第6期595-597,594,共4页 Practical Oncology Journal
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