黄曲霉毒素B1和赭曲霉毒素A对商品肉鸡IBD疫苗免疫的影响

Effect of Aflatoxins B1 or Ochratoxin A on Infectious Bursal Disease Vaccinal Immunity in Commerical Broilers

通过在每千克商品肉鸡饲料中分别添加黄曲霉毒素B1(AFB1)和赭曲霉毒素A(OA)100μg、200μg以及同时添加黄曲霉毒素B1和赭曲霉毒素A各100μg,与对照组比较两种毒素对商品肉鸡IBD疫苗免疫抗体的影响。采血监测结果证实:在18、30、36、45d,AFB1-100、OA-100组与对照组比较IBD疫苗免疫ELISA抗体效价没有明显降低,没有产生明显的免疫抑制,差异不显著(P>0.05);AFB1-200组,OA-200组、F/O-200组与对照组比较IBD疫苗免疫ELISA抗体效价都显著降低,差异极显著(P<0.01),产生了明显的免疫抑制。研究为商品肉鸡生产者控制商品肉鸡IBD的发生提供了一定的参考依据。

This study campared antibody titer by immunized with vaccine against IBD between experimental groups and control groups in Ross commerical broilers during aflatoxins B1 （AFB1）,ochratoxin A （OA）and AFBI Or OA. Experimental groups add separately 100 μg/kg and 200 μg/kg of aflatoxins B1 （AFB1） or ochratoxin A （OA） in feeds of Ross commerical broilers on 1-day-old to 36-day-old,and add 100 μg/kg of both mycotoxins separately at the same time, The results indicated that no obvious imraunosuppression existed after immunized with vaccine against IBD （P〉0.05）in experimental groups AFB1-100 and OA-100 on 18,30,36,45 d,and obvious imunodesuppression existed （P〈0.01） in experimental groups AFB1-200,OA-200 and F/O-200 on the same days. The results provide some data for controlling IBD in commerical broilders.