基于外标记的图像配准在放射免疫显像图像融合中的应用

Application of external fiducial frame-based image registration in the fusion of radioimmunoimaging

目的:本研究旨在验证外基准标记物在肿瘤患者单光子发射计算机断层术(single photon emission computed tomo-graphy,SPECT)放射免疫显像与CT图像融合中的临床应用价值。方法:将外标记物固定于6例肿瘤患者背部体表后,分别行SPECT放射免疫显像和CT扫描,并行图像配准融合。结果:6例患者的放射免疫显像图像能够精确地与CT图像进行融合,肿瘤病灶定位准确。结论:通过外标记物配准可以实现放射免疫显像与解剖显像图像进行融合,提高诊断定位的精确性。

Objective ： To validate the clinical value of external fiducial frame in the fusion of single photon emission computed tomography （SPECT） radioimmunoimaging and CT imaging in tumor patients. Methods： The external fiducial frame was fixed on the body surface of back of the 6 patients. SPECT radioimmunoimaging and CT scan were performed on the 6 patients. The two styles of image were fused on the PC computer. Results： The images produced by SPECT radioimmunoimaging of the 6 patients were exactly fused with the CT image. The tumor lesions were correctly focused. Conclusion： The fusion of radioimmunoimaging and anatomic imaging would be accomplished by using the external fiduciat frame. Image fusion increases the accuracy of location diagnosis.