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经皮介入和局部溶栓治疗急性肺栓塞临床研究 被引量:1

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摘要 目的评价用普通经皮冠状动脉成形术(PTCA)导引导管经皮介入和局部溶栓治疗急性肺栓塞的疗效和安全性。方法对46例急性肺栓塞患者经肺动脉造影确诊后即刻用普通PTCA导引导管行肺动脉内碎栓、吸栓及尿激酶溶栓治疗,观察处理前后的肺动脉压,血氧饱和度和症状改善情况。结果46例急性肺栓塞患者处理前后肺动脉压从(57.23±6.21)mmHg(1mmHg=0.133kPa)降至(36.34±4.05)mmHg(P〈0.01),血氧饱和度从(81.41±4.32)%升至(97.01±2.02)%(P〈0.01),症状明显改善,无出血、血管破裂、死亡等严重并发症。结论普通PTCA导管经皮介入结合局部溶栓治疗急性肺栓塞,能迅速改善临床症状、降低肺动脉压和提高血氧饱和度,未发现明显并发症,安全有效。
出处 《中国医师杂志》 CAS 2008年第11期1513-1514,共2页 Journal of Chinese Physician
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