丹参川芎嗪注射液治疗急性心肌梗死的疗效观察

Observation on the Effect of Danshen Chuanxiongqin Injection on Acute Myocardial Infarction

目的观察丹参川芎嗪注射液治疗急性心肌梗死的疗效及安全性。方法将93例急性心肌梗死患者随机分为观察组和对照组,两组均给予常规治疗,观察组在此基础上,加用丹参川芎嗪注射液静滴,连用14d。结果观察组和对照组的总有效率分别为84.8%和63.8%,两组比较差异有统计学意义(P<0.05)。观察组在治疗后的肌酸激酶较对照组明显下降(P<0.001),且降至正常所需时间也明显缩短(P<0.001)。未见明显药物不良反应。结论丹参川芎嗪注射液治疗急性心肌梗死疗效肯定,不良反应少。

Objective To observe the therapeutic effect and safety by injecting Danshen Chuanxiongqin into the patients with acute myocardial infarction（AMI）. Method 93 cases with AMI were randomly divided into the treatment group and the control group. The two groups were received regular drugs. In addition, the treatment group intravenously received Danshen Chuanxiongqin injection for 14 days. Results The total effectiveness rate of the treatment group was significantly higher than that of the control group （84.8 % vs 63.8 %, P 〈 0.05 ）. After treatment, the creatine kinase of the treatment group was significantly dropped than that of the control group and the time that the ereatine kinase dropped to normal level was shortened than the control group （both P 〈 0.001 ）. No remarkable side effects occurred during the treatment. Conclusion Danshen Chuanxiongqin injection is effective for treating AMI and has little side reaction.