期刊文献+

胃肠道间质瘤16例临床分析

下载PDF
导出
摘要 目的探讨胃肠道间质瘤的临床表现、诊断、治疗和预后。方法回顾性分析1999年4月-2007年7月收治的16例胃肠道间质瘤的临床和病理资料。结果主要临床表现为腹部不适(8/16),消化道出血(6/16);病变部位为胃14例,十二指肠1例,小肠1例。14例行手术治疗。16例镜下均见梭形细胞,其中良性9例,交界性4例,恶性1例,胃癌伴良性间质瘤1例。免疫组化CD11(7+)73%,CD3(4+)73%,SMA(-)73%,S-100(-)67%。结论内镜和影像学检查是发现胃肠道间质瘤病变的主要手段,术前确诊仍较困难,手术切除是病理确诊和治疗的主要方法。
作者 李迎春
出处 《基层医学论坛》 2008年第32期993-994,共2页 The Medical Forum
  • 相关文献

参考文献5

二级参考文献19

  • 11,Kindblom LG,Remotti HE,Aldeborg F,et al.Gastrointestinal pacemaker cell tumor (GIPACT):gastrointestinal stromal tumors show phenotypic characteristics of the interstitial cells of Cajal.Am J Pathol,1998, 152:1259~1269.
  • 22,Damatteo Bp, Lewis JJ,Leung D,et al.Two hudred gastrointestinal stromal tumors: recurrence patterns and prognostic factors for survival.Ann Surg,2000,231:51~58.
  • 33,Lasota J,Jasinski M,Sarlomo-Rikala M,et al.Mutation in exon 11 of c-kit occur preferentially in malignant versus benign gastrointestinal stromal tumors and do not occur in leiomyomas or leimyosarcomas.Am J Pathol,1999,154:53~60.
  • 44,Pross M,Manger T, Schulz HU ,et al.Gastrointestinal stromal tumors -problems in diagnosis and therapy.Chirurg,1999,70:807~812.
  • 55,Gloeckner K,Rudolph P,Feller AC, et al.Prognostic factors for gastrointestinal stromal tumors.Verh Dtsch Ges Pathol,1998,82:253~260.
  • 6Seidal T, Edvardsson H. Expression of c-kit(CD117) and Ki67 provides information about the possible cell of origin and clinical course of gastrointestinal stromal tumors. Histopathology, 1999, 34:416-424.
  • 7Mazur MT, Clark HB. Gastric stromal tumors. Reappraisal of histogenesis. Am J Surg Pathol, 1983, 7: 507-519.
  • 8Kindblom LG, Remotti HE,Aldenborg F,et al. Gastrointestinal pacemaker cell tumor(GIPACT):gastrointestinal stromal tumors show phenotypic characteristics of the interstitial cells of Cajal. Am J Pathol,1998,152:1259-1269.
  • 9Hirota S,Isozaki K,Moriyama Y, et al. Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science, 1998, 279:577-580.
  • 10Miettinen M, Lasota J. Gastrointestinal stromal tumors-definition,clinical,histological,immunohistochemical,and molecular genetic features and differential diagnosis. Virchows Arch,2001,438:1-12.

共引文献284

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部