芒果苷小檗碱组合物降血糖作用的试验研究

Experimental Study on Hypoglycemic Effect of the Mixture of Mangiferin and Berberine

目的:探讨芒果苷小檗碱组合物(MMB)的降血糖作用。方法:采用肾上腺素和葡萄糖所致高血糖小鼠模型、以及四氧嘧啶糖尿病小鼠模型,观察MMB对试验动物的降血糖效果。结果:MMB对四氧嘧啶所致糖尿病小鼠有明显的治疗效果,对肾上腺素和葡萄糖引起的高血糖模型小鼠也有明显的降血糖作用,但对正常小鼠的血糖无明显影响。结论:MMB对高血糖模型小鼠有明显的降血糖作用,但对正常小鼠血糖无明显影响。

Objective： To study the hypoglycemic effect of the mixture of Mangiferin and Berberine （MMB）. Methods： Experimental observation was performed by using various diabetic mice induced by Alloxan, adrenalin and glucose. Redsults： MMB could significantly lower the blood glucose levels in Alloxan model mice, adrenalin model mice and hyperglycemic mice, while had no hypoglycemic effect on the normal mice. Conclusion： MMB has hypoglycemic effect in diabetic model mice.