X线对胎儿期成骨不全的诊断价值

X-ray Value in Diagnosis of Osteogenesis Imperfecta of Fetus

目的评估X线对胎儿期成骨不全的诊断价值。资料与方法回顾性分析6例死胎成骨不全的X线征象。结果4例为Ⅱ型成骨不全,表现为四肢长骨短粗、弯曲变形、骨小梁结构紊乱,肋骨短小变形,胸廓狭小,颅骨薄。2例为Ⅲ型成骨不全,表现为四肢长骨细长,多发骨折,肋骨、胸廓未见明显异常。其中1例母亲为Ⅰ型成骨不全。结论X线平片可以明确胎儿期成骨不全X线诊断和分型,为临床提供重要诊断依据。

Objective To evaluate the diagnostic value of X-ray in osteogenesis imperfecta of fetus. Materials and Methods X-ray findings of 6 dead fetus with osteogenesis imperfecta were analyzed retrospectively. Results Four cases with the type II osteogenesis imperfeeta were characterized by severe shortened and widened long bones and ribs, narrow thorax. Two cases with the type III osteogenesis imperfeeta were characterized by multiple fractures with low bone density and thin cortical bone. X-ray findings of 6 cases were corresponded with findings in autopsy. One fetus＂ mother was a patient with the type I osteogenesis imperfecta. Conclusion X-ray image is critical to diagnose different types of osteogenesis imperfeeta of fetus and provid important evidences for clinic diagnosis,inherited consultation and genie Diagnosis.