运动型乳饮料的抗疲劳作用

THE ANTIFATIGUE EFFECT OF A SPORT MILK DRINK

目的观察运动型乳饮料对小鼠的抗疲劳作用,为研制新型抗疲劳功能乳饮料提供科学依据。方法小鼠随机分成对照组、牛奶组和饮料低、中、高3个剂量组。对照组给予纯净水,牛奶组给予市售某品牌牛奶,低、中、高剂量组分别按小鼠每公斤体质量2.5、5、10 g剂量灌胃。每鼠日灌胃量每10 g体质量0.2 mL,共30 d。测定负重游泳时间、尿素氮(BUN)、血乳酸(LAC)和肝糖原(LG)。结果低、中剂量饮料组小鼠负重游泳时间分别为(425±117)s和(410±89)s,明显长于对照组〔(243±60)s,P<0.05〕;并且运动后血清尿素氮水平分别为(7.41±1.11)mmol/L和(7.44±1.80)mmol/L,显著低于对照组〔(9.01±1.29)mmol/L,P<0.05〕;低、中和高剂量饮料组肝糖原分别为(0.37±0.07)mg/g(、0.40±0.14)mg/g和(0.35±0.11)mg/g,明显高于对照组〔(0.17±0.07)mg/g,P<0.05〕;低剂量饮料组运动后血乳酸水平为(2.90±1.02)mmol/L,显著低于对照组〔(3.71±1.51)mmol/L,P<0.05〕。结论此运动型乳饮料对增强运动耐力和消除疲劳具有一定的的作用。

Objective To observe the antifatigue effect of a sport milk drink on mice, so as to provide scientific basis for developing a new functional antifatigue drink. Methods Mice were randomly divided into 5 groups：3 groups treated with sport milk drink of 2.5,5, 10 g/kg bw respectively, control group with purified water, and ordinary milk group.The solution was administered to the mice with a daily dose of 0.2 mL/10 g bw for 30 d. Load swimming test was then carried out. And serum urea, blood lactic acid as well as liver glycogen level were measured. Results The average load swimming time in low and medium dose treated groups [ （425 ± 117） s, （410 ± 89） s respectively ] was longer than that in control group [ （243± 60）s, P 〈 0.05 ]. Serum urea concentration in treated groups [ （7.41 ± 1.11 ） mmol/L, （7.44± 1.80）mmol/L respectively] was lower than that in control group [（9.01 ±1.29）mmol/L, P 〈0.05]. Liver glycogen content was significantly higher in 3 treated groups [ （0.37 ± 0.09）mg/g, （0.40 ±0.14） mg/g, and （0.35 ± 0.11） mg/g respectively] than in control group [（0.17±0.07） mg/g, P 〈0.05） Blood lactic acid level [（ 2.90±1.02）mmol/L] in low dose treated group was lower than that in control group [（3.71 ±1.51）mmol/L, P 〈0.05 ]. Conclusion The sport milk drink could improve sport endurace and relieve fatigue to some extent.