慢性乙型肝炎中医证素研究

A research on syndrome key factor in patients with chronic hepatitis B

目的:探讨慢性乙型肝炎中医证素特征及其演变规律。方法:选择慢性乙型肝炎、早期肝硬化、肝硬化腹水患者为研究对象,以面对面访谈的调查方法收集临床资料,统计受损的脏腑、病性证素,并分析其证素演变规律。结果:慢性乙型肝炎损伤的脏腑主要有肝、胆、脾、胃、肾、三焦等,其中肝、脾是其主要的受损脏腑,随着病情进展,脾、肾、三焦、胆、胃受损频率均增加;单纯慢性乙型肝炎患者以气虚、气郁、湿为多;早期肝硬化患者以湿、气虚、气郁、热、血瘀为多;肝硬化腹水患者以湿、血瘀、气虚、水为多。结论:慢性乙型肝炎在病位及病性证素上均有自身的特点和演变规律。

Objective： To discuss the character and evolving rule of the syndrome key factors of chronic hepatitis type B. Methods： First, choose patients of chronic hepatitis type B, early hepatocirrhosis and ascites caused by hepatocirrhosis as objects of the research and then collect clinical information face to face from them, sort out the characters of syndrome key factors and damaged Zang-Fu organs ; Third, analyze the evolving rule of the syndrome key factors. Results： There are liver, gallbladder, spleen, stomach, kidney and trijiao mainly damaged in chronic hepatitis type B, during which liver and spleen are mostly damaged. As the state of the disease＇s developing, the frequency of spleen, kidney, Trijiao, gallbladder and stomach damage increases. Qi-deficiency, qi-stasis and dampness are more common in simple chronic hepatitis type B; dampness, qi-deficiency, qi-stasis, heat and blood stasis are more common in early hepatocirrhosis; dampness, blood stasis, qi-deficiency and dampness are more common in ascites caused by hepatocirrhosis. Conclusion： There are characters and evolving rules of its own in focuses and syndrome key factors in chronic hepatitis type B.