摘要
新化学实体（NCEs）的发现加速了整个二十世纪的进程。这些产品的知识产权主要被市场中高度集中的大玩家所掌控。想要在市场中立足的中小型企业（SMEs）则很难生存。
The discovery of new chemical entities （NCEs） accelerated throughout the course of the twentieth centuryThe intellectual property of these products was predominantly owned by a higher concentration of big players in the market. Life was tough for small to medium sized enterprises （SMEs） trying to gain a foothold in the market.
