液基细胞学在子宫颈病变筛查中的诊断价值

Evaluation of Liquid Based Cytology Test and TBS Cytology Subdivision in Screening of Cervical Lesion

目的评价液基细胞学在宫颈癌前病变早期诊断中的价值。方法采用贝塞斯达(TBS)诊断系统对3227例经宫颈/阴道液基薄层细胞学检查(TCT)的标本进行分析,部分病例经组织学对比印证。结果不典型鳞状细胞(ASCUS)以上异常228例(7.1%):ASCUS119例(3.69%),低度上皮内瘤变(L-SIL)79例(2.44%),高度上皮内瘤变(H-SIL)18例(0.56%),鳞癌(SCC)9例(0.28%),不典型腺细胞(AGUS)3例(0.09%)。其中66例细胞异常者行病理活检,CIN2以上病变两种检测方法的符合率为92.6%(25/27)。结论液基细胞学检查为一种准确、简便的宫颈早期病变筛查方法,可作为宫颈癌防治的有效工具。

Objective To analyze and evaluate the liquid-based test in clinical diagnosis of cervical lesion screening. Method 3227 cases of the liquid-based test results with TBS cytology subdivision and a comparison of histopathology were evaluated. Result In the results of the 3227 cases, 228（7.1%） were positive： 119（3.69%）of ASC, 79 （2.44%） of L-SIL, 18 （0.56%） of H-SIL, 9 （0.28%）of Squamous cell carcinoma and 3 （0.09%）of AGCUS. 66 cases were histopathological diagnosed： 25 cases were diagnosed as CIN II or higher grade, with 92.6% consistent ratio with cytology inspection. Conclusion Liquid-based cytology test can be an effective diagnostic screening of cervical lesions.