原发性肝癌术后复发行经皮肝穿刺新型射频治疗的疗效分析

ANALYSIS OF PERCUTANEOUS HEPATIC PUNCTURE RADIOFREQUENCY ABLATION IN THE TREATMENT OF PRIMARY LIVER CANCER RECURRENCE

目的观察原发性肝癌术后复发行经皮肝穿刺新型射频治疗的疗效,探讨新型射频在治疗原发性肝癌术后复发的应用。方法在B超引导下,将射频电极针经皮穿刺入肝肿瘤内,对其进行原位毁损消融。结果28例患者共34个病灶中:直径≤3cm的23个瘤体,21个完全毁损,热毁损率为91.3%;直径为3～5cm的11个瘤体中8个瘤体获得完全毁损,热毁损率为72.7%。术后无严重并发症发生。术后6、12个月无瘤生存率分别为75%、53.6%;术后6、12、18个月生存率分别为100%,96.4%,92.9%。结论经皮肝穿刺射频消融术对于原发性肝癌术后复发疗效可靠,是一种安全、有效治疗肝癌术后复发的方法。

Objective To observe the elect of percutaneous hepatic puncture radiofrequency ablation in the treatment of primary liver cancer recurrence and to investigate the use of PRFA. Methods Guided by ultrasound, radiofrequency electrodes were percutaneously introduced into the tumor of the liver for ablation in situ. Results Among the 34 tumors in 28 patients, the effective rate of the tumor with diameter ≤3cm was 91.9% （21/23）, With diameter 3 ～ 5cm 72.7% （8/11 ） , No RFA related to severe complications occurred. The 6 month and 12 month of Disease-free survival rates were 75% and 53.6%. The 6 month,12 month and 18 month survival rates were 100% ,96.4% ,92.9%. Conclusion PRFA treatment is effective for primary Liver cancer recurrence. It is a safe and effective approach in treating primary liver cancer recurrence