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彩超评价糖尿病患者下肢动脉病变影响因素 被引量:1

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摘要 目的通过彩色多普勒检测早期糖尿病病人的下肢血管病变,并寻找影响糖尿病病人下肢血管病变的影响因素。本研究对象分为两组,糖尿病组和健康对照组。两组对象均采用单盲法进行研究,其年龄分布、性别组成均具有可比性。方法本研究采用美国GEVivid7pro彩色多普勒超声诊断仪,探头频率为4.0~11.0MHZ。将下肢动脉分为8个节段,所有患者均进行双侧下肢动脉彩色多普勒超声探查。二维超声显像并横切测量动脉管径、内一中膜厚度(IMT)、动脉硬化斑块厚度及计算管径狭窄率。彩色血流图及脉冲多普勒观察动脉内血流充盈状况,测量并记录收缩期峰值流速(PSV)和舒张末期流速(EDV)。所有数据采用统计软件SPSS10.0分析。结果糖尿病组的两个亚组及健康对照组,三组之间比较分析:管腔内径、管壁厚度及管径狭窄率均有明显差异,病程越长动脉病变越严重。结论病程的长短可能会影响糖尿病患者下肢动脉异常的发生率。无下肢临床症状的糖尿病患者也存在下肢血管的异常变化,糖尿病组病人的动脉管径,动脉管壁厚度,管径狭窄率都显著大于健康对照组。以动脉管壁厚度为应变量,生化指标为自变量,多元逐步回归分析表示TG为对动脉管壁厚度有显著意义的决定因素。彩色多普勒超声应成为糖尿患者下肢动脉病变诊断和狭窄分级的首选。
作者 闫卫 赵磊
出处 《医药论坛杂志》 2008年第22期22-23,共2页 Journal of Medical Forum
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参考文献9

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