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转化生长因子-β_1微血管密度在肝纤维化的表达

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摘要 目的研究转化生长因子-β1及MVD在肝纤维化形成过程中的作用及意义。方法采用免疫组织化学方法检测慢性病毒性肝炎、肝纤维化、肝硬化中TGF-β1及MVD的表达。结果随着慢性病毒性肝炎、肝纤维化及肝硬化的形成,TGF-β1表达逐渐增强(P<0.01),MVD在肝纤维化组织中表达高于慢性病毒性肝炎及肝硬化组织。结论肝脏中TGF-β1及MVD的表达与肝纤维化及肝硬化的形成密切相关,可作为诊断治疗肝纤维化的重要指征。
出处 《医药论坛杂志》 2008年第22期35-36,共2页 Journal of Medical Forum
基金 郑州市科技发展计划(攻关计划)2007-15-5
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