盐酸舍曲林对伴焦虑症状高血压患者的血压和生活质量的影响

The clinical Effects of Zoloft on essential hypertension patients with Anxiety

目的探讨盐酸舍曲林对伴焦虑症状高血压患者血压和生活质量的影响。方法对200例高血压患者进行焦虑自评量表（SAS）评分，伴焦虑症状患者随机分为治疗组（苯磺酸氨氯地平片＋盐酸舍曲林片）及对照组（苯磺酸氨氯地平片），无焦虑症状患者列为无焦虑组（苯磺酸氨氯地平片）。观察治疗6周后三组患者降压效果及生活质量评分。结果治疗组、无焦虑组较对照组降压效果差异显著，治疗组SAS评分显著低于对照组，生活质量评分显著高于对照组。结论盐酸舍曲林治疗伴焦虑症状高血压患者能提高降压疗效，降低高血压患者焦虑的严重程度，提高生活质量。

Objective To investigate the clinical effects of Zoloft on essential hypertension subjects with anxiety. Methods After evaluating 200 cases with essential hypertension by SAS, the subjects with positive results who were followed for 6 weeks from baseline assessments were randomly divided into experimental group （Norvasc and Zoloft）and control group（ only Norvasc）and the subjects with negative results were regarded as non-anxiety group. The effects of reduce blood pressure, the scores of SAS and quality of life were compared among 3 groups. Results In experimental groups and non-anxiety groups, the effects of reduce blood pressure significantly better than those of control group. The scores of SAS in experimental groups were significantly lower and the scores of quality of life were significantly higher than those of control groups. Conclusion Zoloft on Essential Hypertensive subjects with anxiety could significantly improve clinical outcome, and also lower the degree of psychological obstacle, improve quality of life of essential hypertension patients.