肺吸虫病32例临床病理分析

Clinical and pathological characteristics of paragonimiasis in 32 patients

目的探讨毕节地区肺吸虫病临床病理学特征。方法对32例肺吸虫病进行回顾性临床资料分析及病理形态学观察。结果32例肺吸虫病的共同病理学特征:切面有多发坏死腔穴和窦道;镜下病灶中坏死腔穴及窦道为凝固性坏死,可见夏科-雷登结晶体,部分可见幼虫体;坏死周围有嗜酸性粒细胞浸润。结论毕节地区肺吸虫病以儿童为主(93%);皮下结节型多见(97%),无其他疫区常见肝、脑等内脏型病变。肺吸虫病有独特病理学特征,病理检查是肺吸虫病最主要的诊断方法。

Objective To discuss the chnical and pathological features of paragonimiasis in Bijie area of Guizhou provence. Methods The clinical characteristics and gross and microscopic features were analysed in 32 cases of paragonimiasis. Results 32 cases of paragonimiasis had the uniform pathological features： there were many nodes with cavities and sinus in the subcutaneous tissue; the coagulation necrosis could be seen in the cavities and sinus, and Charcot-Leiden＇ s crystal and larvae were observed in some cases; the eosinophil was infiltrated around the coagulation necrosis. Conclusion The patients with paragonimiasis are mainly children in Beijie area of Guizhou provence （93%） ; the frequent type is subcutaneous nodules （97%）. Paragonimiasis has particular pathological features, and therefore pathological examination is the most important diagnostic method for paragonimiasis.