用MetriScan^(TM)骨密度仪测量西双版纳、西藏、内蒙古地区健康人群骨密度的情况调查分析

Investigation on bone mineral density in normal group in XiShuangBanNa,Tibet and Inner Mongolia

目的应用放射吸收法测量云南西双版纳、西藏和内蒙古三个少数民族地区,对傣族、藏族和蒙古族健康人群的骨量分布差异和峰值骨量进行调查分析,为临床诊断骨质疏松提供参考。方法选择云南西双版纳傣族健康男女1126名,年龄20～79岁。西藏藏族健康男女1531名,年龄20～79岁。内蒙东乌旗蒙古族健康男女901名,年龄20～79岁。以10岁为一年龄段进行分组。用美国Alara公司提供的MetriscanTM指骨骨密度仪,进行骨密度测量。数据采用SPSS软件包进行统计学分析。结果西双版纳傣族男女、西藏藏族男女和内蒙古东乌旗蒙古族女性的峰值骨年龄段均在30～39岁,蒙古族男性峰值骨年龄段在40～49岁。傣族和藏族男性骨量丢失12%以上在60～69岁年龄段,蒙古族男性70～79年龄段骨量丢失11.04%。傣族女性50～59岁年龄段骨量丢失达20.80%,藏族女性为13.67%。蒙古族女性丢失12%以上在60～69岁年龄段。三个民族不同年龄段骨密度值比较,男性除藏族和蒙古族20～39岁年龄段没有差异外,其余各年龄段均有显著性差异。女性除傣族和藏族20～29岁年龄段没有差异外,其余各年龄段均有显著性差异。结论健康成人傣族男性与藏族和蒙古族健康成人男性相比骨密度有显著差异,藏族和蒙古族男性40岁以后骨密度均值有显著性差异。傣族女性与蒙古族女性各年龄段骨密度均有显著性差异,傣族与藏族女性30岁后骨密度有显著性差异。其差异是种族、地域,还是生活习性引起有待进一步研究。

Objective To observe the bone mineral density variation and define age of the peak bone mass of normal group in Dai, Tibetan and Monolian nationalities in XiShuangBanNa, YunNan province, Tibet and Inner Mongolia, and find the regularity of loss. To provide a reference for clinical osteoporosis diagnostic criteria. Methods Select 1126 healthy Dai people in XiShuangBanNa, 1531 Tibetans in Tibet and 901 Mongolian people in Inner Mongolia respectively, which aging from 20 to 79 and was grouped by gender and 10 year age segment. Measured the bone density on 2nd,3rd and 4th fingers of the less frequently used hand by the MetriScan offered by Alara Company and calculated the mean bone density. The data was processed and analyzed by the software SPSS 11.0. Results The average age appearing peak bone density is 30 - 39 in Dai people, Tibetans and Mongolian females, but 40 - 49 in Mongolian males. The Dai and Tibetan males aging 60 - 69 lose bone rate over 12%, yet the Mongolian males aging 70 - 79 only lose 8.53 % . The Dai females aging 50 - 59 lose bone rate20.80 %, and the Tibetan females lose 13.67%, yet the Mongolian females aging 60 - 69 lose over 12% bone mass. It is obvious that Dai females have earlier loss than Tibetan and Mongolian females, the Mongolian males is late in loss than Dai and Tibetan males, while the Dai males is equal to Tibetan males. Compare the mean bone density value of different age group among the three races. In males, all the age group varies significant except Tibetan and Mongolian males aging 20 - 39. In females, all the age group varies significant except Dai and Tibetan females aging 20 - 29. Conclusion There is a significant difference of bone density between Dai males and Tibetan, Mongolian males, which can be observed between Tibetan and Mongolian males older than 40. Meanwhile, there is also significant difference between Dai, Tibetan females and Mongolian females, which can be observed between Dai and Tibetan females older than 30. Further research needs to define the variation cause, race, geography or diet difference？