胶质细胞在神经病理性痛中的作用

Effects of neuroglia cells on neuropathic pain

长期以来,慢性疼痛的"神经元论"占据了统治地位。但近年来,随着疼痛研究的不断深入,神经胶质细胞在神经病理性痛中的作用引起人们的关注。研究发现,胶质细胞在神经病理性痛中的发生和维持中起着非常重要的作用。以胶质细胞为靶点的镇痛药物的开发将开创疼痛治疗一个崭新的时代。

For a long time, the ＂neuronism＂ of chronic pain is dominant. Recent years, however, the effect of neuroglia cells on neuropathie pain has already been noted with the development of the research on pain. It is found that neuroglia ceils play a very important role in inducing and maintaining neuropathic pain. So, to develop a kind of pain agent targeting at neuroglia cells may open a new epoch of pain treatment.