新生儿先天性甲状腺功能减退症筛查中TSH切值的探讨

Exploration of cut-off value of TSH during screening of congenital hypothyroidism in the newborns

新生儿筛查中发现，TSH水平与先天性甲状腺功能减退症（CH）检出率呈直线正相关。当TSH切值点分别为9、10、15和20mU／L时，CH阳性检测敏感度分别为99．77％、96．80％、81．25％和71．88％。TSH〉9mU／L是较好的切点。

Positive linear correlation was found between TSH level and detection rate of congenital hypothyroidism （CH）. When measured with a cut-off point at 9, 10, 15 and 20 mU/L of TSH, the sensitivity of positive detection rate for CH was 99.77%, 96.80%, 81.25% and 71.88%, respectively. TSH 〉 9 mU/L seems to be a reasonable cut-off value.