糖尿病肾病“微型癥瘕”病理假说解析

Explanation and analysis on TCM pathology hypothesis micro-zhengjia of diabetic nephropathy

在整理古代文献的基础上,参照现代医学相关认识,结合临床实际,提出糖尿病肾病"微型癥瘕"病理假说,认为糖尿病肾病的发生、发展,实质上是糖尿病治不得法,迁延不愈,伤阴耗气,痰、郁、热、瘀互相胶结,积聚于肾之络脉,形成微型癥瘕,由瘕聚渐成癥积的过程。正气亏虚为肾生癥瘕之因,痰热郁瘀互结为肾生癥瘕之关键。临证时应抓住"微型癥瘕"这一共性病理环节,及早治疗,在辨证施治的基础上,强调活血化瘀、软坚散结治法,以阻止其"微型癥瘕"的形成,防止瘕聚不断发展成癥积。"微型癥瘕"病理假说的提出,丰富和发展了中医治未病理论。

By studying the ancient literature and referring to the relevant understanding of modern medicine,combining with clinical practice, we proposed micro-zhengjia TCM pathology hypothesis of diabetic nephropathy. The onset and development causes for Diabetic nephropathy is the delay and the improper treatment of diabetes, which leaded the injury of the yin and qi, the cementation of the sputum, yu, heat and blood stasis in the kidney collaterals which is called micro-zhengjia. Treatment should focus on the general pathology links - micro-zhengjia, emphasize the use of activate blood and resolve stasis treatment in order to prevent the formation of micro-zhengjia. The pathology hypothesis proposed, enriched and developed the theory of preventive treatment.