急性白血病长期生存34例分析

THE LONG-TERM SURVIVAL OF 34 CASES OF ACUTE LEUKEMIA

目的探索影响急性白血病长期生存的因素。方法对急性白血病患者诱导缓解期采用强烈而有效的联合化疗，并实行个体化用药原则，坚持缓解后正规的巩固强化治疗，长期随访观察，根据情况调整用药方案。结果急性白血病２６９例中达到完全缓解２０２例（７５％），３ａ以上长期生存３４例（１７％）。结论影响急性白血病长期生存的主要因素为急性白血病类型、个体化治疗、达到完全缓解的时间长短、正规的缓解后治疗等。

Objective To investigate the factors affecting the long-term survival of acute leukemia (AL). Methods Intensive combined chemotherapy was administered under the principle of individualization to induce remission.Regular consolidation treatment after remission was continued strictly. Long-term follow-up was kept on,with the therapeutic regimen modified accordingly. Results Complete remission (CR) was achieved in 202 of 269 (75%) AL patients and 34 (17%) of them had survived more than 3a. Conclusion The long-term survival of AL patients is related to the type of AL, individualized therapy, time required to achieve CR and the regular postremission treatment.