摘要
采用犬心脏停跳后复苏动物模型，观察了浅低温对犬脑缺血再灌后酶代谢及脂质过氧化的影响。结果表明：浅低温可促进脑内Ｎａ＋－Ｋ＋ＡＴＰ酶和ＬＤＨ活性的恢复，保护ＳＯＤ活性和降低ＭＤＡ含量，减少ＧＳＨ的丧失。
The effect of mild hypothermia on Na^+-K^+-ATPase and lipid peroxidation in canine brain tissue following a 18minute cardiac arrest and resuscitation for 8 hours were studied. Mild hypothermia improved the restoration of the activity of Na^+-K^+-ATPase, LDH, protect the activity of SOD, decrease the loss of GSH, but not completely blocked the ischemia reperfusion induced lipid peroxidation.
出处
《湖南医科大学学报》
CSCD
1998年第1期8-10,共3页
Bulletin of Hunan Medical University
关键词
浅低温
脑缺血
再灌注损伤
脂质过氧化
ATP酶
hypothermia
induced
reperfusion injury
brain
Na^+-K^+- ATPase
lipid peroxidation
