101例小儿肾活检病理与临床研究

Relationship between clinical manifestationand pathology in pediatric renal diseases

对１０１例临床诊断为１３种肾脏疾病的小儿采用快速经皮肾活检病理学检查。结果表明：肾活检成功率为１００％；最常见的病理类型为ＭｓＰＧＮ；临床表现类似的疾病病理类型不同，同一病理类型，临床表现可以多样。提示肾活检病理诊断对肾脏疾病的诊断、治疗。

To elevate the clinical diagnosis and pathological compatibility of pediatric kidney diseases. Pathological changes from 101 cases of pediatric renal diseases were studied, covering 13 diseases entities, including glomerulo-nephritis, simple nephrotic syndrome, nephritic nephrotic syndrome etc. Renal biopsy was used the technique of trucut biopsy under the guidance of B ultrasonogram. The renal puncture biopsy was 100% satisfactory. Pathological changes involved 12 pathological types. MsPGN were the most commonly seen(39.6%), followed by MPGN and ICPGN(12.87% and 10.89%) respectively. It was found that children with similar clinical manifestation may possess different pathological changes, while the same pathological entity may present multiple clinical manifestation. The results suggest that renal biopsy pathological diagnosis is important in the diagnosis, treatment and prediction of prognosis in pediatric renal disease.