慢性荨麻疹患者血清抗幽门螺杆菌抗体的检测及意义

Detection of serum IgG antibodies against Helicobacter pyloru and its clinical significance in patients with chronic urticaria

为探讨幽门螺杆菌（helicobacterpylori，Hp）感染在慢性荨麻疹中的作用，作者采用间接ELISA技术检测了26例慢性荨麻疹患者的血清抗Hp抗体。结果显示：26例慢性荨麻疹患者中有17例血清抗HpIgG抗体阳性，应用根除Hp感染的方案治疗2月后，17例阳性患者有12例获得痊愈。由此考虑Hp感染可能与部分荨麻疹的发生有关。

In order to study the possible role of Helicobacter pylon (HP) in patients with chronic urticaria, the serum specific IgG antibodies against HP in 26 cases of chronic urticaria were detected by indirect enzyme-linked immunosorbent assay (ELISA). The results showed that serum specific IgG antibodies against Hp were positive in 17 of 26 patients with chronic urticaria, and eradication of Hp was accompanied by clinical remission in 12 of 17 cases. It is concluded that Hp infection may be related to part of patients with chronic urticaria.