摘要
采用电镜酶细胞化学（AcP酶）方法观察了γ射线照射后大鼠肝细胞内自噬体的一系列变化特征，特别是线粒体的降解，及此过程中自噬体的形成和自噬体与溶酶体之间的相互关系。结果显示，照射后大鼠肝细胞产生大量自噬体，受损线粒体被自噬后，溶酶体参与其降解过程。
By using enzyme-cytochemical method for acid phosphatase and transmission electron mi croscopy,the characteristics of the sequential alterations of autophagic vacuoles (AV) were observed after γ-irradiation in rat hepatic parenchymal ce1ls,especially the processes of mitochondrial degradation and the relationship between AV and lysosomes. The results showed that Y-irradiation caused high frequency of AV formation,and lysosomes participated in the degradation of AV.
出处
《第一军医大学学报》
CSCD
1998年第1期1-3,共3页
Journal of First Military Medical University
基金
国家自然科学基金!39470347
关键词
Γ射线
线粒体降解
酶学
肝细胞
大鼠
γ-irradiation
mitochondria
autophagosome
enzyme-cytochemistry
