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米非司酮联合米索前列醇多次用于终止早孕的观察 被引量:3

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摘要 目的观察米非司酮联合米索前列醇多次应用于终止早孕的效果观察,评价其可行性及注意事项。方法回顾性分析3年在我站进行多次药流的460例患者的临床资料。结果完全流产88.04%、不全流产9.78%、失败2.17%;前次药物流产平均阴道流血时间为(8.2±1.8)天,本次为(8.7±2.1)天,差异无显著性(P<0.05),月经量均与以往月经量相似;前药流转经时间平均为(28.8±5.7)天,本次为(29.7±6.2)天,两者间无显著性差异(P<0.05);部分出现胃肠道反应均可忍受,无需处理,自行缓解;流产2周后复查血红蛋白、凝血功能及血小板计数,均与用药前无明显变化。结论米非司酮联合米索前列醇多次终止早孕的不全流产和失败的发生率较高,但完全性流产仍达88.04%;阴道流血时间、转经时间平均与前次药物流产者比较有延长,但无统计学意义,药物不良反应轻,临床上具有可行性,但应注意掌握适应证、加强流产后的管理。
出处 《中国现代药物应用》 2009年第1期123-124,共2页 Chinese Journal of Modern Drug Application
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