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内皮细胞相关黏附分子的研究进展 被引量：4

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摘要 白细胞黏附于血管内皮细胞并渗出内皮细胞层是免疫反应的关键和重要步骤。此过程不仅需要激活白细胞及其膜表面黏附分子,而且需要内皮细胞上相关的黏附分子的调控。目前研究已由研究黏附生理过程转向研究此过程的分子机制。本文主要介绍与此过程相关的内皮细胞黏附分子的基因表达、信号转导通路调控以及对细胞功能的影响等的最新研究进展。
作者 张宇 桑晨 庄逢源
机构地区 北京航空航天大学生物与医学工程学院
出处 《细胞与分子免疫学杂志》 CAS CSCD 北大核心 2009年第1期89-91,共3页 Chinese Journal of Cellular and Molecular Immunology
基金 国家自然科学基金资助项目(10672013)
关键词 内皮细胞 细胞黏附分子 白细胞渗出 信号转导
分类号 R392.11 [医药卫生—免疫学]
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参考文献15

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同被引文献35

  • 1黎晓,龚妍春.整合素及其信号转导通路的研究进展[J].赣南医学院学报,2007,27(1):153-154. 被引量：6
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  • 8Long M, Huang SH, Wu CH, et al. Lipid raft/caveolae signaling is required for Cryptococcus neoformans invasion into human brain microvascular endothelial cells[J]. J Biomed Sci, 2012, 19(1): 19.
  • 9Suzuki M, Kobayashi H, Fujie M, et al. Kunitz-type protease inhibitor bikunin disrupts phorbol ester-induced oligomerization of CD44 variant isoforms containing epitope v9 and subsequently suppresses expression of urokinase-type plasminogen activator in human chondrosarcoma cells [J]. J Biol Chem, 2002, 277 (10): 8022-32.
  • 10Huang SH, Long M, Wu CH, et al. Invasion of cryptococcus neoformans into human brain microvascular endothelial cells is mediated through the lipid rafts-endocytic pathway via the dual specificity tyrosine phosphorylation-regulated kinase 3 (DYRK3) [J]. J Biol Chem, 2011, 286(40): 34761-9.

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细胞与分子免疫学杂志
2009年 第1期

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