摘要
为了寻找生物活性成分,采用色谱分离法对望谟崖摩和曲枝崖摩进行了化学成分研究。根据波谱学分析鉴定了化合物结构。从两种植物中分离得到了15个化合物,分别为8(17),13(E)-半日花-二烯-15,19-二酸(1),8(17),13(E)-半日花-二烯-19-酸甲酯-15-醛(2),15-O-乙酰基-8(17),13(E)-半日花-二烯-19-酸(3),15-羟基-8(17),13(E)-半日花-二烯-19-酸(4),15,19-二羟基-8(17),13(E)-半日花-二烯(5),19-羟基-8(17),13(E)-半日花-二烯-15-醛(6),19-羟基-8(17),13(Z)-半日花-二烯-15-醛(7),8(17),13(E)-半日花-二烯-19-酸-15-醛(8),8(17),13(Z)-半日花-二烯-19-酸-15-醛(9),(+)-儿茶素(10),β-香树素(11),豆甾-5-烯-3β,7α-二醇(12),东莨菪内酯(13),β-谷甾醇(14),胡萝卜苷(15)。上述化合物均为首次从崖摩属植物中分离得到的半日花烷型二萜。
The phytochemical investigations on Amoora ouangtliensis and A. stellato-squamosa were conducted in order to look for bioactive compounds. Nine diterpenoids were obtained by the method of column chromatography, and on the basis of spectral analysis they were identified as 8 ( 17 ), 13 (E) -labdadien-15,19-dioic acid ( 1 ), methyl 8 ( 17 ), 13 (E) - labdadien-19-oic acid-15-oate ( 2), 15-acetoxy-8 ( 17 ), 13 (E) -labdadi-en-19-oic acid ( 3 ), 15-hydroxy-8 ( 17 ), 13 (E) - labdadien-19-oic acid ( 4), 8 ( 17 ), 13 (E) -labdadien- 15,19-diol ( 5 ), 19 -hydroxy-8 ( 17 ), 13 (E) -labdadien-15-al ( 6 ), 19-hydroxy-8 ( 17 ), 13 (Z) -labdadien-15-al (7) ,8 ( 17 ), 13 (E) -labdadien-19-oie acid-15-al (8), 8 ( 17 ), 13 (Z) -labdadien-19-oic acid-15-al ( 9 ), and six other compounds, ( + ) -catechin ( 10 ), β-amyrin ( 11 ), stigmast-5-en-3β, 7α-diol (12), scopoletin(13) ,β-sitosterol( 14), daucosterol(15). This is the first report of labdane-type diterpene from the genus Amoora.
出处
《天然产物研究与开发》
CAS
CSCD
2008年第6期1000-1004,共5页
Natural Product Research and Development
基金
This project was supported by the National Science Foundation of China(NSFC,20602037).
关键词
望谟崖摩
曲枝崖摩
半日花烷二萜
Amoora ouangtliensis
A. stellato-squamosa
labdane-type diterpene