摘要
目的:分析抗骨质疏松药物引起不良反应的原因。方法:检索国内外期刊2000~2008年有关抗骨质疏松药物所致不良反应的个案报道及综述。结果:抗骨质疏松药物的不良反应发生率不高,程度较轻,常见于胃肠道不适。结论:可通过合理配伍,联合用药来减少不良反应发生率;如长期用药,其安全性需密切关注。
OBJECTIVE:To analyze the causes of adverse drug reactions (ADRs) induced by anti-osteoporosis drugs. METHODS: Individual case reports and review articles about the anti-osteoporosis drug-induced ADR reported in journals both at home and abroad during the period 2000 - 2008 were retrieved. RESULTS:The incidence of anti-osteoporosis druginduced ADRs was low and the degree was light, which manifested chiefly as discomfort of gastrointestinal tract. CONCLUSION:The reduction of the incidence of anti-osteoporosis drug-induced ADRs relies on rational combination and combined drug use. Great attention should be attached to the safety of anti-osteoporosis drugs if used for a long term.
出处
《中国医院用药评价与分析》
2008年第12期950-951,共2页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
抗骨质疏松药物
不良反应
回顾性分析
Anti-osteoporotic drugs
Adverse drug reaction
Retrospective analysis