摘要
目的:进一步认识小儿心内膜纤维弹力组织增生症的临床病理学特征。方法:收集我院3例尸检及1例心内膜心肌活检病例,结合临床病史、心电图、心脏超声心动检查及病理学常规及特殊染色。结果:心脏形态学改变,表现为心脏增大,质量增加,以左心室增大为主,右心室也可增大;心内膜呈弥漫或不规则增厚。光镜下,心内膜弹力纤维及胶原纤维明显增生,平行排列呈十余层,弹力纤维染色阳性。结论:本病预后差,病理诊断应与心内膜心肌纤维化病进行鉴别,必要时做心内膜活检确诊。
Objective： To investigate the clinicopathological features of endocardial fibroelastosis （EFE） in children. Methods： Three autopsy cases and one endocardial biopsy case were collected. The clinical data included electrocardiogram, echocardiography, histopathologic and special stain. Results： All of 4 cases had cordismicphological changes, dominating changes were augmentation of left ventrical. It was found the diffused or anomalistic incrassation of endocardium. The main histopathologic feature was the endocardial thickening due to proliferation of elastin and collagen. Histochemical staining of elastin was positive. Conclusion： It is suggested that EFE should be differentiated from the endocardial myofibrosis. It is necessary to do the endomyocardial biopsy.
出处
《现代生物医学进展》
CAS
2008年第12期2288-2290,2297,共4页
Progress in Modern Biomedicine
基金
卫生部科研课题(WKJ2007-3-001)
