摘要
目的建立小儿清热宁颗粒中黄芩苷的含量方法。方法采用高效液相色谱(HPLC)法测定小儿清热宁颗粒中黄芩苷的含量。结果 HPLC法测得本品中黄芩苷的含量为0.648～0.652mg/m1,在0.40～2.00μg/ml的范围内,溶液的浓度与峰面积呈良好的线性关系,r=0.9998,加样回收率为99.76%(n=5),RSD为0.9%。结论本品定量方法简便、准确、专属性强,能够控制该制剂的内在质量。
Objective Study on the quality standarded for Xiaoer qingrening Keli. Method Radix Scutellariae , Flos Lonicerae in Xiaoer qingrening Keli were identified by TLC, and the content of Baicalin was determined by HPLC. Result The Baicalin showed a good linear relationship within a range of 0.40 - 2. 00ug/ml （ r = 0.9998 ）, the average recovery was 99.76% （ n = 5 ）, RSD = 0.9 %. Conclusion HPLC is accurate and reliable method . The quality standard can be used for quality control of this product.
出处
《中国医学创新》
CAS
2008年第36期27-28,共2页
Medical Innovation of China
