伴大豆球蛋白水解肽对鸭抗大肠杆菌感染的作用

The effect of hydrolysates from conglycinin on the host defense against E. coli O_(78) infections in duck

研究灌服伴大豆球蛋白水解肽的麻鸭,在肌肉注射大肠杆菌O78后的健康状况,并分析有关细胞因子水平的变化。结果表明,感染对照组出现典型的大肠杆菌病病理变化,而灌服伴大豆球蛋白水解肽的鸭只临床症状较轻。与感染对照组比较,伴大豆球蛋白水解肤能显著提高鸭脾脏IL-2水平与肠道黏膜slgA水平,显著降低脾脏TNF-α水平,说明伴大豆球蛋白水解肽能提高动物机体免疫机能,抵御外源性大肠杆菌的侵袭感染,预防胃肠道疾病的发生。

This study was to detect the health and analysis levels of spleen IL-2, slgA and TNF-α of duck fed conglycinin hydrolysates after intramuscularly administering with E. coli O78. The result showed that typical pathological symptoms of colibacillosis appeared in the infection control group and the clinical symptoms in each tested group were slighter. Compared with infection control group, the conglycinin bydrolysates significantly increased levels of spleen IL-2 and intestinal slgA concentration, and significantly decreased spleen TNF-α level. The result indicated that hydrolysates from conglycinin could increase the immune function in duck, defend the invasion of E. coli and keep the gut healthy.