3Paul Brown,Raymond Bradley. 1755 and all that: a historical primer of transmissible spongiform encephalopathy[J]. Practical Neurology, 1998,317 : 1688-1692.
5Martin H Groschup, Patricia A McBride. Deposition of disease-associated prion proteininvolves the peripheral nervous system in experimental scrapie[ J]. Acta Neuropathol, 1999, 98 : 453-457.
7Richard H, Kimbertin, Carol A. Pathogensis of scrapie (strain263K) in hamsters infected Intracerebrally, Intraperitoneally or Intraocularly[J]. Journal of General Virology, 1986, 67:255-263.
8Michael Beekes,Patricia A Mcbride, Elizabeth Baldquf. Cerebral targeting indicates vagal spread of infection in hamsters fed with scrapie[J]. Journal of General Virology, 1998, 79: 601-607.
9Achim Thomzig,Christine Kratzel. Widespread prpsc accumulation in musckes of hamsters orally infected with scrapie[J]. EMBO reports, 2003,4 (5) : 530-533.
10Loredana Ingrosso, Flavio Pisani, Maurizio Pocchiari. Transmission of the 263K scrapie strain by the dental route[J]. Journal of general virology, 1999,80 : 3043-3047.
2Zhao Y, Swenson K, Sergio J J, et al. Skin graft tolerance across a discorant xenogenetic barrier. Nat. Med., 1996.2(11): 1211 ~ 1216.
3Zhao Y, Rodriguez-Barbosa J I, Swenson K, et al. The induction of specific pig skin graft tolerance by grafting with nenonatal pig thymus in thymectomized mice. Transplantation,2000.69(7): 1447 ~ 1451.
4Khan A, Sergio J J, Zhao Y, et al. Discordant xenogenetic neonatal thymic transplantation can induce donor-specific tolerance.Transplantation, 1997.63 ( 1 ): 124 ~ 131.
5Nikolic B, GardnerJP, ScaddenDT, etal. Normaldevelopment in porcine thymus grafts and specific tolerance of human T cells m porcine donor MHC. J. Immtmol, 1999.162(6): 3402 ~ 3407.
6.家兔[EB/OL].http:∥www.hblac.com/tz.htm,.
7Chae S J, KramerAD, Zhao Y, et al. 1999. Lack of variation αgal expression on lymphocytes m miniature swine of different genotypes.Xenotransplantation, 1999.6:43 ~ 51.
8Gritsh H A, Glaser R M, Emery D W, et al. The importance of nonimmuce factors in reconstitution by discordant xenogenic hematopoietic cells. Transplantation, 1994.57(6): 906 ~ 917.
9Lee L & Gritsch H A, Sergio J J, et al. Specific tolerance across a discordant xenogemc transplantation barrier. Proc. Natl. Acad. Sci.USA, 91(23): 10864 ~ 10867.
9Russell WMS, Burch RL. The Prmciples of Humane Ex- perimental Technique [ M ]. London : Methuen, 1959.
10Chang S, Multani AS, Cabrera NG, et al. Essential role of limiting telomeres in the pathogenesis of Werner syn- drome [ J ]. Nat Genet ,2004,36 ( 8 ) : 877 - 882.