摘要
目的:研究木瓜抗氧化作用及抗氧化作用机制。方法:采用邻苯三酚自氧化法、DPPH法、Fenton反应法检测木瓜提取物对体外超氧阴离子自由基(O-2·)、DPPH活性氧自由基、羟自由基(·OH)的清除作用以及对小鼠心、肝、肾、血清超氧化物岐化酶、过氧化脂质、肝过氧化物酶等指标。结果:木瓜提取物可以有效清除O-2·、DPPH·、·OH等自由基,并对小鼠血清、心、肝、肾脂质过氧化物的升高有明显抑制作用,可提高其超氧化物岐化酶,过氧化酶的活性。结论:木瓜黄酮有较好的抗氧化作用。
Objective： To study on the anti-oxidation effects and mechanism of Chaenomeles sinensis fruit extracts. Methods： Pyrogallol auto-oxidation method, Fenton reaction and DPPH methods were used to detect antioxidation properties in vitro, and the activity of supeioxide dismutase （SOD）, malondialdehyde （MDA）in the serum, heart, liver and kidney and liver peroxidase （POD） of the mice administered with different doses of the extracts by gavage were measured in vivo. Results： The Chaenomeles sinensis fruit extracts have strong O2·, ·OH and DPPH o radicals, scavenging activity. They have preventive effect on the rise of lipid peroxide and improve the SOD activity. The results suggested that pawpaw flavoind is a potential antioxidant and （POD） activiy.Conclusion： The extracts have excellent antioxotion properties.
出处
《食品科学》
EI
CAS
CSCD
北大核心
2008年第12期645-648,共4页
Food Science
