临床麻醉中常用中效肌肉松弛剂的比较

Comparative Study of Common Mid-effect Muscle Relaxants in Clinical Anesthesia

为了更准确在临床麻醉过程中使用中效肌肉松弛剂,用比较治疗学的理念及方法对目前国内报道的中效肌肉松弛剂阿曲库铵、顺式阿曲库铵、维库溴铵、罗库溴铵的应用方法进行比较和分析。结果发现:插管起效时间罗库溴铵最短,临床时效顺式阿曲库铵最长,阿曲库铵有组胺释放的作用,阿曲库铵和顺式阿曲库铵药物代谢主要是霍夫曼消除。比较治疗学方法有助于临床麻醉肌松剂的抉择。

To apply mid-effect muscle relaxants more accurately in clinical anesthesia, we retrospectively analyze the reported domestic application methods of mid-effect muscle relaxants for example Atracurium, Cis-atraeurium, Vecuronium, and Rocuronium. The clinical decision-making is guided by the comparative study principle and methodology. Rocuronium＇ s onset time in endotracheal intubation is the shortest,Cis-atracurium＇ s clinical aging is the longest, Atracurium has the role of histamine release,Atracurium and Cis-atracurium,s drug metabolism rely on the elimination of Hoffman. Comparative Study contributes to the clinical choice of narcotic muscle relaxant.