血清绒毛膜促性腺激素及孕酮检测在妊娠早期中的诊断及治疗意义

Themeaning of combined progesterone and β-HCG in treatment and dignoses of early pregnancy

目的探讨血清孕酮与绒毛膜促性腺激素联合检测在妊娠早期中的诊断及治疗意义。方法分别采用ECL／RIA技术对300例早期妊娠者血清孕酮与绒毛膜促性腺激素进行检测。结果血清P值〉60nmol／L，血β－HCG〉50mIU／ml患者85例，占28．33％，经卧床休息，未用药治疗，均胚胎发育正常；血清P值在30-60nmol／L，血β-HCG10—50／mIU／ml患者155例，占51．67％，经黄体酮与绒毛膜促性腺激素保胎治疗后均胚胎发育正常；血清P值〈30nmol／L，血β-HCG〈10mIU／ml患者45例，占15％，终止妊娠者均可见清除宫内组织物中几乎不见新鲜绒毛并伴有不同程度的陈旧性出血；血清孕酮与β-HCG上升不同步患者15例，占5．0％，均最终难免流产。结论对于妊娠早期者动态观察血清孕酮与β—HCG，对于妊娠结局的预测及指导治疗具有重要的临床价值。

Objectve： To discuss the clinical meaning of combined progesterone （P） and β-HCG in treatment and dignoses of early pregnancy. Methods： Using ECL and RIA technique to examine serum p and β - HCG concentration in 300 early pregnancy. Results： There were 85 patients （28. 33% ） whose serum P 〉60nmol/L and β- HCG 〉50mIU/ml, after had rest on bed without any drug all could develop with nomal fetus; There were 155 patients （51.67%） whose serum P 30 -60nmol/L and β - HCG10 - 50mlU/ml, with the treatment of lutein and HCG, all could develop nomally; There were 45 patients （ 15% ） whose serum P 〈 30nmol/L and β - HCG 〈 10mIU/ml and there were 15 patients （ 15% ） whose serum p and 13 - HCG were asynchronous. Conclusion： There is sigenificant clinical value to examine P and β - HCG in treatment and dignoses of early pregnancy.